Niacinamide vs Vitamin C: Key Differences, How to Layer & Use Them Together

Vitamin C, also known as ascorbic acid, is a powerful antioxidant that fights free radical damage, brightens dull skin, and boosts collagen production. Think of it as your go-to for morning skincare—it helps protect against pollution and sun damage while giving your skin that lit-from-within glow. If uneven skin tone or fine lines bother you, vitamin C serum benefits like brightening and anti-ageing properties are worth every drop.

Niacinamide, or vitamin B3, is like the calm, soothing best friend your skin needs. It strengthens the skin barrier, reduces redness, and keeps oiliness in check—all without irritating sensitive skin. Plus, niacinamide serum benefits include minimising pores and improving overall skin texture, making it a dream ingredient for anyone battling breakouts or rough patches.

Before combining them, it helps to understand the difference between niacinamide and vitamin C. Here's a quick breakdown:

When it comes to skincare, both Vitamin C and Niacinamide are star ingredients, but they work in slightly different ways. Vitamin C is best known for its brightening properties and ability to tackle hyperpigmentation while boosting collagen production, making it a go-to for dull, uneven skin. On the other hand, Niacinamide is incredibly versatile—reducing redness, strengthening the skin barrier, controlling oil, and improving texture, making it perfect for sensitive or breakout-prone skin. Texture-wise, Vitamin C often comes in lightweight serums that feel refreshing, while Niacinamide formulas tend to be soothing and hydrating, blending well into most skincare routines. In short, Vitamin C gives you that radiant, lit-from-within glow, while Niacinamide calms, repairs, and refines the skin over time.

Absolutely, yes! For years, there was a myth that mixing niacinamide and vitamin C cancels out their benefits, but that's long been debunked. Here's why they actually work beautifully together:

• Double Brightening Power: Vitamin C fades dark spots while niacinamide prevents new ones from forming.
• Stronger Barrier + Glow: Niacinamide calms skin so vitamin C can work without irritation.
• Balanced Effect: Vitamin C's acidic nature and niacinamide's soothing properties complement each other.
• Layer-Friendly: You can layer them in the same routine or use one in the AM and the other in the PM.

To make the most of your niacinamide and vitamin C serum, follow these steps:

1. Cleanse: Start with a gentle face wash like Simple Refreshing Face Wash to remove dirt and oil.

2. Tone (Optional): Apply a hydrating toner if you like.

3. Apply Vitamin C First: Use a brightening serum like Simple Vitamin C Serum or Pond's Anti-Pigmentation Serum on clean, dry skin in the morning. Let it absorb for 1–2 minutes.

4. Follow with Niacinamide: Apply Simple 10% Niacinamide + Pro-Vit B5 Booster Serum to calm skin and strengthen the barrier.

5. Moisturise: Lock it all in with a hydrating moisturiser like Simple Protect N Glow Vitamin C Moisturising Glow Gel.

6. SPF Always: Vitamin C makes your skin photosensitive, so never skip sunscreen.

Pro Tip: If you have sensitive skin, use Vitamin C in the morning and niacinamide at night instead of layering them together.

• Vitamin C:

• If your main goal is to brighten dull skin.
• If you're targeting dark spots or pigmentation.
• If anti-ageing is a priority.

• If you have acne-prone or oily skin.
• If your skin barrier feels damaged or irritated.
• If you want to reduce pore size and redness.

Many people benefit from using both together, but if you want to start slow, pick one based on your primary skin concern.

• Using too high concentrations: Start with lower percentages to avoid irritation.

• Skipping sunscreen: Vitamin C without SPF = wasted effort.

• Mixing too many actives: Don't combine with strong exfoliating acids initially.

• Not checking pH levels: Use well-formulated products; don't DIY these ingredients.

• Layering too quickly: Allow each serum to absorb before the next step.

Using niacinamide and vitamin C serum together can transform your skincare routine when done right. Vitamin C delivers radiance, niacinamide keeps things calm and balanced—together, they're the dream team for glowing, healthy skin. With the right products, you can build an effective, fuss-free routine that actually works.

Yes, if your skin tolerates it well. Start slow—alternate days at first.

Vitamin C first, then niacinamide, because vitamin C works best on bare skin.

Not recommended. Layer them one after the other for best results.

Vitamin C works best in the morning, niacinamide can be used both AM and PM.

Consistent use for 6–8 weeks usually brings visible improvement.