Best Serums for Oily Skin: Dermatologist-Approved Picks and How to Use Them Effectively

Serums are lightweight, fast-absorbing formulations designed to deliver concentrated ingredients deep into the skin. Unlike heavy creams, the best face serums for oily skin are non-comedogenic (won't clog pores) and can actually help balance sebum production. According to dermatologists, serums formulated with actives like niacinamide, vitamin C, and retinol are excellent tools to keep oily skin in check—without stripping it dry.

Unlock the secret to balanced, radiant skin without the shine.

• Lightweight hydration without clogging pores: Serums absorb quickly, delivering moisture without heaviness or greasy residue.
• Pore minimization: Ingredients like niacinamide help reduce the appearance of enlarged pores for smoother skin.
• Helps balance sebum production: Controls excess oil, keeping skin fresh and shine-free without over-drying.
• Acne prevention and treatment: Targets acne-causing bacteria with ingredients like salicylic acid and tea tree oil.
• Refines skin texture and tightens pores: Promotes cell turnover and collagen for a firmer, more even complexion.
• Boosts glow without greasiness: Antioxidants and vitamins brighten skin for a natural, healthy radiance.
• Potential anti-aging benefits: Supports elasticity and reduces fine lines with hydrating and firming ingredients.

When it comes to oily skin, choosing the right serum can be overwhelming. That's why we've turned to dermatologists to highlight the most effective ingredients tailored to your skin's unique needs. Whether you're battling acne, struggling with enlarged pores, or seeking a healthy glow without excess oil, these expert-approved ingredients have you covered.

Niacinamide (vitamin B3) is a multitasking ingredient that regulates oil production, reduces the appearance of enlarged pores, and calms inflammation. This makes it ideal for anyone looking for an open pores serum for oily skin or something to manage shine throughout the day.

How it works: Niacinamide supports the skin barrier, tightens pores, and reduces acne-causing inflammation.

Use it: Morning and evening after cleansing. Layer before moisturizer.

Pro Tip: Pair with a gentle cleanser like Novology Acne Deep Clearing Cleanser to reduce pore congestion and prep the skin for better serum absorption.

Looking for a way to brighten up dull skin without clogging your pores? A lightweight vitamin C serum for oily skin delivers antioxidant protection while evening out your skin tone. It's particularly effective if your oily skin is also prone to post-acne pigmentation or dullness.

How it works: Vitamin C neutralizes free radicals, fades dark spots, and promotes collagen production—without adding oil.

Use it: Best in the AM to protect your skin from environmental stressors.

Pro Tip: Always apply sunscreen over your vitamin C serum to maximize protection and results.

Retinol, a derivative of vitamin A, is one of the most dermatologist-recommended ingredients for treating oily, acne-prone, and aging skin. A retinol serum for oily skin helps unclog pores, smooth rough texture, and reduce fine lines—all while promoting skin turnover.

How it works: It increases cell turnover, regulates sebum production, and prevents clogged pores.

Use it: Apply in the PM only, 2–3 times a week. Always follow with a non-comedogenic moisturizer.

Caution: Start with a low concentration (0. 25–0. 5%) to avoid irritation and always wear SPF during the day.

If you're battling active breakouts, look for a targeted serum for acne-prone oily skin. Ingredients like salicylic acid, tea tree oil, and zinc are popular choices—but one dermatologist-approved pick includes the Novology Acne Serum. Lightweight and fast-absorbing, it works to clear blemishes while calming inflammation.

How it works: Formulated to unclog pores, kill acne-causing bacteria, and reduce post-acne marks.

Use it: Nighttime is best for targeted acne serums. Apply directly on breakouts or all over if acne is persistent.

Bonus Tip: Use with Novology Acne Deep Clearing Cleanser for a complete blemish-fighting routine.

Begin by washing your face with a gentle cleanser to clear away dirt, oil, and impurities. Follow up with a toner to balance your skin and help the serum absorb better.

Take a small amount of serum—just a few drops or about the size of a pea—and gently pat it onto your face and neck. Avoid rubbing harshly; instead, use light tapping motions, focusing especially on areas where oiliness or breakouts are common. Let the serum fully sink in before moving on.

Once the serum has absorbed, finish with a lightweight, oil-free moisturizer to keep your skin hydrated without adding extra shine.

Look for key ingredients that work well with oily skin, such as:

• Salicylic Acid: Helps exfoliate and clear clogged pores.
• Niacinamide: Controls oil production and shrinks pores.
• Hyaluronic Acid: Delivers hydration without heaviness.
• Vitamin C: Protects against damage and brightens your complexion.

One of the most common questions asked is how and when to apply serum for oily skin—and it does make a difference. Here's the correct order of application:

Morning Routine:

1. Cleanser: Use a gentle, gel-based or foaming cleanser.
2. Toner (Optional): Choose an alcohol-free one for pH balance.
3. Serum: Apply a few drops of a lightweight, water-based serum like Simple 10% Niacinamide + Pro-Vit B5 Booster Serum to help control oil, reduce pores, and soothe the skin.
4. Moisturizer: Go for a gel or oil-free formula.
5. Sunscreen: Always finish with SPF 30 or higher.

Night Routine:

1. Cleanser: Use a makeup and oil-removing cleanser.
2. Toner (Optional):
3. Serum: Apply retinol or acne treatment serums.
4. Moisturizer: Finish with a hydrating yet non-greasy night cream.

Pro Tips:

• Don't mix retinol and vitamin C at the same time; use them in separate routines.
• Always patch-test a new serum to avoid breakouts or irritation.

1. Less is More: One or two serums per routine is enough.
2. Consistency is Key: Results take time. Use your serum daily for at least 4–6 weeks.
3. Check the Texture: Opt for water or gel-based serums for quick absorption.
4. Go Fragrance-Free: Fragrance can sometimes trigger irritation on oily, sensitive skin.

Final Thoughts

So, which serum is best for oily skin ? It depends on your skin's needs—whether it's oil control, acne treatment, brightening, or anti-aging. The key is to pick serums with proven ingredients like niacinamide, vitamin C, and retinol, and use them consistently. With dermatologist-backed options and smart layering, serums can help transform oily skin into a balanced, glowing complexion. Looking for a reliable start? Try the Novology Acne Clearing Serum for blemish control and pair it with the Novology Acne Deep Clearing Cleanser for optimal results. Remember, skincare isn't about quick fixes—it's about building smart, science-backed habits that last.

Q: Is serum good for oily skin? Yes, especially when using lightweight, non-comedogenic formulas. They help control oil, prevent acne, and improve skin texture. Q: Which serum is best for oily skin? The best serum for oily skin depends on your specific concern. For oil control, use niacinamide. For brightening, opt for vitamin C. For acne, try a targeted treatment like Novology Acne Serum. Q: Can I use multiple serums at once? Yes, but limit to 1–2 per routine. Use vitamin C in the morning and retinol or acne treatments at night. Q: Can I skip moisturizer if I'm using serum? No—serums treat, but moisturizers seal everything in. Choose a lightweight one designed for oily skin.